> The thymus is the primary organ of the immune system
> It shrinks with age, increased cortisol, starvation, and dietary PUFA
> It can be revitalized with aromatase inhibitors, including zinc
> Zinc reduces infection rates in older people
“It is therefore possible to restore the thymus in intact aging rats without recourse to surgical or chemical castration.”
“Aging-related physiological zinc deficiency induces some relevant changes in thymus structure and function which can be partially corrected by a mild oral zinc supplementation.”
"Cortisol treatment resulted, within two days, in a loss of lymphocytes (in thymus) and a rise in the proportion of macrophages and fibroblasts. This pattern was similar to that characteristic of old thymus, except that the loss of lymphocytes was greater after cortisol injection and there was no increase in collagen.”
“Our study showed that zinc supplementation administered to the elderly population resulted in a significant decrease in the incidence of infection.”
“Zinc deficiency, cell-mediated immune dysfunction, susceptibility to infections, and increased oxidative stress have been observed in elderly subjects.”
“Many animal studies show that zinc deficiency decreases resistance to a range of bacterial, viral, fungal, and parasitic pathogens, probably because of the immune impairment induced by zinc deficiency.”
from https://x.com/lowmegatron/status/1898400973619367999
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